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Oxidative stress refers to an imbalance between the production of reactive oxygen species (ROS) and the body's ability to neutralize or repair the resulting damage. It occurs when excess ROS, such as free radicals, are generated, overwhelming the antioxidant defenses of the body.

Reactive oxygen species are normal byproducts of cellular metabolism and are involved in various physiological processes within the body. However, when their production surpasses the body's antioxidant capacity, they can cause damage to cellular components like proteins, lipids, and DNA, leading to oxidative stress.

Factors that can contribute to oxidative stress include environmental pollutants, certain medications, poor diet, exposure to radiation, excessive physical exercise, and various diseases. Additionally, lifestyle choices like smoking, excessive alcohol consumption, and chronic stress can also exacerbate oxidative stress.

Oxidative stress has been associated with numerous health conditions, including neurodegenerative diseases (such as Alzheimer's and Parkinson's), cardiovascular diseases, diabetes, inflammatory conditions, and certain types of cancer. It is thought to contribute to the aging process and the development of chronic diseases.

To counteract oxidative stress, the body employs a complex system of antioxidants, including enzymes (such as superoxide dismutase, catalase, and glutathione peroxidase) and non-enzymatic antioxidants (such as vitamin C, vitamin E, and glutathione). Maintaining a healthy lifestyle, consuming a balanced diet rich in antioxidants, engaging in regular physical activity, and reducing exposure to environmental toxins are important in managing oxidative stress.

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Oxidative Stress

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